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Women with PCOS face a 2.8-fold higher risk for obesity and a 1.7-fold higher risk for central obesity compared with individuals without PCOS ( AOMs, including liraglutide and semaglutide, combined with lifestyle intervention could offer an upgraded treatment strategy for patients with PCOS and obesity ( Even though GLP-1 RAs seem to have a great potential to improve obesity-related metabolic and reproductive complications in PCOS, their use is currently not widely acknowledged and accepted in this population