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Data or Concepts to Include: Article states evidence is stronger for topical skin and specific wound-related studies

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When evaluating adipose tissue in WT and 3-KO mice, researchers found that neither treatment significantly affected white adipose tissue mass in either genotype

The changes occurring in vivo , when labeled RBC are re-introduced into the circulation By far the most direct method to study in vivo aging of RBC is their biotinylation by N-hydroxysuccinimide-biotin and analyzing the properties of the biotinylated RBC during their life span in circulation by collecting the labeled RBC on avidin at various times after injection (Suzuki and Dale, 1987