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Arthritis-related elbow pain often requires targeted therapies to preserve joint health and function

Melanotan-2 remains the only available pharmacological tool allowing the simultaneous study of the relative contributions of the four MCR receptors using selective antagonism protocols (HS024 for MC4R, JNJ-10229570 for MC3R, etc.)

GLP-1 receptor activation primarily promotes glucose utilization and glycogen storage while reducing hepatic glucose production

2 Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia 3 Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia 4 ShemyakinOvchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia 5 Institute of Functional Genomics, Lomonosov Moscow State University, 119991 Moscow, Russia * To whom correspondence should be addressed