Indeed, there may be synergy between FGF-21 and GCG receptor agonism, due to their similar metabolic actions, particularly related to brown adipose tissue differentiation and activation [32], with FGF21 having additional actions in the liver, reducing hepatic lipogenesis and enhancing hepatic insulin sensitivity [66, 67]
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We also found that the acupuncture protocols used in clinical trials lack consistency, which may be related to the diversity of acupoint selection and compatibility, heterogeneity of operating parameters and stimulation techniques, diversity of acupuncture methods, and lag in mechanism research and standardization
A., Zhang, J., Nikolic, M., et al