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As one review notes, enzymes in GSH biosynthesis maintain intracellular ROS detoxification, and their inhibition sensitizes cells to oxidative stress

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Available online: 36.Cignarella A., Busetto L., Vettor R

Water concentrations were calculated based on the volume fractions of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF), assuming their water concentrations as 35,880 mM, 43,300 mM, and 55,556 mM, respectively [52]