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It is of great interest for its effects and ability to induce sleep, especially in chronic insomnia, release pain, reduce oxidative stress, enhance muscle building, normalize of myocardial contractility, and is also being investigated as a possible agent in the treatment of depressive disorder and withdrawal symptoms

The mechanism involves attraction of immune cells and mesenchymal stem cells to wound sites, along with stimulation of glycosaminoglycan production and decorin synthesis, both of which are critical for proper extracellular matrix assembly

doi: 10.3389/fnins.2022.836605 Received 15 December 2021 Accepted 04 February 2022 Published 25 February 2022 Volume 16 - 2022 Edited by Dilshan Shanaka Harischandra, Covance, United States Reviewed by Amy Shepherd, Boston Childrens Hospital and Harvard Medical School, United States

Anaphylactic shock and death have been reported after parenteral Vitamin B12 administration