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Scientists need to understand the difference between NAD and peptides to classify them correctly in biochemistry and develop targeted treatments that make use of information about their unique properties

Although this difference in the gut microbiome is in part driven by standard of therapy used in treatment of cirrhosis and HE (such as oral antibiotics, NADs, and acid suppressants) which can affect the gut microbiome composition, 33 cross-sectional data of stool metagenomics have revealed that certain metagenomic species are overexpressed or underexpressed in decompensated compared to compensated cirrhosis

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