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The goal of treatment is to limit any worsening of your curvature or scarring, increase blood flow into the penis, and treat penile pain

Taking doses too close together may increase stomach upset

Snaebjornsson, M

Factors that might warrant dose adjustment include body weight (with some research using weight-based dosing of 0.5-1.0 mcg/kg), response to first doses (with increases if effects are suboptimal or decreases if adverse effects occur), research phase (with possible dose increases in later phases of long-term protocols), and mix with other research compounds (which may need dose adjustments to account for combined effects)