This IR cascade initiates a characteristic sequence of metabolic and oxidative perturbations within mitochondria: succinate accumulation during ischemia, reverse electron transport-driven ROS generation upon reperfusion, calcium overload, opening of the mPTP, and ultimately, release of mtDAMPs
This low molecular weight protein has been widely utilized due to its excellent biocompatibility, easy biodegradability, and weak antigenicity
10.2174/1568026617666170102125648 [DOI] [PubMed] [Google Scholar] Hassanzadeh P., Arbabi E., Atyabi F., Dinarvand R
Sharon Kumar April 22, 2026 Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available