Anastrozole is an aromatase inhibitor licensed only for hormone receptor-positive breast cancer in postmenopausal women The medication works by blocking oestrogen production, which may actually worsen sexual function when oestrogen levels drop too low in men NICE guidance does not recommend aromatase inhibitors as a treatment option for erectile dysfunction Off-label use in men carries risks including reduced bone density, unfavourable lipid profiles, and potential worsening of sexual function Evidence-based ED treatments include PDE5 inhibitors like sildenafil, lifestyle modifications, and specialist assessment when hormonal imbalance is suspected Table of Contents What Is Anastrozole and How Does It Work
doi: 10.2337/db14-1577 Summary Keywords gut microbiota, GLP-1 receptor agonists, type 2 diabetes mellitus, glycemic response, dysbiosis, GLP-1 resistance Citation Tsai C-Y, Lu H-C, Chou Y-H, Liu P-Y, Chen H-Y, Huang M-C, Lin C-H and Tsai C-N (2022) Gut Microbial Signatures for Glycemic Responses of GLP-1 Receptor Agonists in Type 2 Diabetic Patients: A Pilot Study
Mazdutide is developed by Innovent Biologics with trials primarily conducted in China
All the studies included people with overweight and obesity and 21 studies enrolled participants with prediabetes or type 2 diabetes
