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semaglutide, liraglutide) require no dose adjustment for mild-to-severe renal impairment per UK SmPCs, but dehydration from gastrointestinal side effects can trigger acute kidney injury (AKI)

Its once-weekly dosing improves patient adherence, while strong clinical outcomes and widespread physician adoption further support its market leadership The type 2 diabetes mellitus is expected to account for the largest share during the forecast period in application market In 2025, the type 2 diabetes mellitus segment is expected to dominate the market with the largest market share of 74.5% due to the widespread adoption of GLP-1 receptor agonists, such as Ozempic and Trulicity, for managing Type 2 diabetes

Indirect Effects on Antiplatelet and Anticoagulant Efficacy GLP-1-induced weight loss and metabolic improvements can shift cardiovascular risk profiles, potentially affecting the ongoing clinical rationale for antiplatelet therapy

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