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There are two main types of thyroid hormone receptors, TR and TR, which form homodimers or heterodimers with other nuclear receptor family members, the retinoid X receptors (RXRs) (Harvey et al

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Safety and tolerability at higher doses appear acceptable based on preliminary data, but long-term experience is limited

Overall, characteristics were similar across the groups except for age being slightly lower in the placebo group, and the use of -blockers being higher in the semaglutide group