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The original phase 3 results of the TRIUMPH-1 trial announced in May showed the drug yielded up to 28% weight loss, with some participants losing up to 85 pounds

When integrated with hormone optimization, nutrition, resistance training, and restorative sleep, microdosing offers a potential pathway to extend healthspan, not just lifespanallowing women to age with energy, cognitive vitality, and cardiovascular resilience.

All of the dynamics around GLP-1s, compounding shortage workarounds, and potential for DTC telehealth fallout I described last August seem to be playing out in 2025

'The [drama] is penetrating me 100%