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Being overweight or obese is often the root cause of chronic diseases, including: Cardiovascular disease Type 2 diabetes Stroke High blood pressure High cholesterol Fatty liver Certain types of cancers Osteoarthritis Sleep apnea Hormone disorders, including insulin resistance Alzheimers or dementia Depression and other mood disorders Joint pain A landmark clinical trial published in The New England Journal of Medicine in 2021 found that semaglutide led to a 15% reduction in body weight, on average

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