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doi: 10.3892/mmr.2021.12416 141 LiG.ZhouJ.WeiJ.LiuB

R., Blackburn, W., Orem, I., and Hughes, J

These co-occurring conditions significantly influence which therapies are most appropriate and how they are delivered

Animal model research reveals remarkable efficacy in both accelerated and natural aging conditions, with XpdTTD/TTD mice (accelerated aging model) showing restoration of multiple age-related deficits including fitness, fur density, and renal function following FOXO4-DRI administration