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Zhang Q, Delessa CT, Augustin R et al (2021) The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

While the MHRA has approved these treatments for adults with a body mass index (BMI) of 30 kg/m or above, or 27 kg/m with weight-related comorbidities, it's important to note that NICE guidance (TA875) specifies narrower criteria for NHS access, particularly for semaglutide, which is typically only available through specialist weight management services

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Effects of liraglutide versus sitagliptin on circulating cardiovascular biomarkers, including circulating progenitor cells, in individuals with type 2 diabetes and obesity: analyses from the LYDIA trial