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Acknowledgments We thank our study volunteers for providing samples and supporting this work and the clinical staff for their dedication to this research
Magnesium is required for the production of adenosine triphosphate (ATP) ( 7 )
This emulation approach allows for causal inference by aligning the observational analysis with the methodological principles of an RCT [25]
For instance, gene editing technologies like CRISPR-Cas9 present exciting possibilities for addressing age-related diseases, but concerns regarding off-target effects, long-term safety, and the ethical implications of genetic modifications need to be thoroughly addressed before such interventions can become mainstream ( Moreover, many of the discussed interventions are currently only accessible to select groups of people, either due to high costs, lack of regulatory approval, or geographical disparities in healthcare infrastructure (Scott et al., 2021)
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