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Patients using topical GHK-Cu alongside metformin can be reassured that no meaningful interaction is expected through this route

Some studies have shown that exendin-(9-39) also binds the GIP receptor (17, 18), however, Schirra and colleagues have demonstrated that doses of exendin-(9-39) that completely antagonize the insulinotropic effects of GLP-1 do not alter the insulinotropic activity of GIP in vivo in humans (16)

While results may vary, speaking with your healthcare provider is the best way to determine if this therapy aligns with your specific health needs and goals

This is why injections are a standard medical treatment for conditions like pernicious anemia, malabsorption syndromes, and deficiencies related to gastrointestinal disease or surgery