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revealed that, although changes within the phylum Firmicutes are heterogeneous, butyrate-producing generasuch as Faecalibacterium, Roseburia, and Coprococcusare significantly reduced, whereas Proteobacteria expanded and Bacteroidetes decreased (Qin et al., 2012), The number of Bifidobacterium (Li et al., 2023) decreased, while randomized studies suggested an increase in Bacteroides (Zhang et al., 2025)

Psychedelics face their own challenges as most remain Schedule I substances, but they offer a cleaner patent landscape with the possibility of broader protection if successful in treating addiction

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The infrared (IR) spectra were run as KBr disk on Perki-Elmer Spectrum RXI FTIR