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37 Similarly, in a retrospective cohort study of 3435 people with type 2 diabetes exposed to tirzepatide for 180 days and over compared with a matched unexposed cohort, tirzepatide was associated with an increased risk of new-onset proliferative diabetic retinopathy primarily in those with pre-existing nonproliferative diabetic retinopathy

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What the data suggest is that all three medications produced meaningful weight loss across premenopausal, perimenopausal, and postmenopausal groups, indicating that GLP-1-based treatments can remain effective regardless of a womans menopause status, shares Dr