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The side effect profiles of both medications are remarkably similar

However, the most important part of the story is also the easiest to lose in a headline: an advisory committee recommendation is not a final FDA decision, and inclusion on a compounding list is not the same as FDA approval of a medication

Bile acids are involved in processes including glucose and lipid metabolism, energy balance, and immune regulation through several key receptors such as the farnesoid X receptor (FXR), Takeda G protein-coupled receptor 5 (TGR5), pregnane X receptor (PXR), vitamin D receptor (VDR), sphingosine-1-phosphate receptor 2(SP1PR2), and retinoid-related orphan receptort (RORt) (Jia et al., 2023)

Manufacturing issues can lead to inconsistent dosages, which may cause negative health issues