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They are mitigated by: Accurate anatomical placement (deep enough into the target muscle, far enough from boundary muscles) Appropriate dilution (concentrated enough to localise but not over-concentrated) Avoiding injection too close to certain landmarks particularly the inferior border of the frontalis when treating forehead, and the inferior orbital rim when treating crows feet Patient post-treatment behaviour (not lying flat, not massaging) for the first 4 hours When complications do occur, they typically resolve as the toxin wears off over 612 weeks there is no permanent effect

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7.3 IGF-1 accelerates collagen production During tendon healing, there is a unique pattern of collagen production