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Neural theory implicates neuromediators and catecholamines, while biochemical theory blames melanogenesis byproducts and other biochemicals in damaging melanocytes

Unlike broad hormonal interventions, peptides are highly targeted

Compounded medications are not FDA-approved but are prepared by pharmacies regulated by state boards of pharmacy

3.3.3 Receptors mediated mitophagy activators Panax notoginseng saponins (PNS), the primary ingredient from Panax notoginseng, exhibits extensive therapeutic effects in cardiovascular diseases (Liu et al., 2014), lung cancer (Yang et al., 2016) and diabetes (Uzayisenga et al., 2014)