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The preclinical signal for BPC-157 is unusually consistent across independent research groups and across a wide range of injury models, pointing toward a compound with genuine biological activity rather than a laboratory artifact
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Via our first nonoxidative reaction, phosphopentose isomerase catalyzes a rearrangement (an isomerization) of ribulose 5-phosphate to ribose 5-phosphate
These effects mirror those observed with exercise, leading to interest in ERR agonists as potential "exercise mimetics." The compound also increases mitochondrial respiration in vitro, consistent with the role of ERRs in regulating mitochondrial function
