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3.1.2 Exenatide As the first GLP-1R agonist approved for T2DM, EX is a new class of compound and a synthetic product of exendin-4, which is a compound naturally derived from the Gila monster and has multiple hypoglycemic mechanisms: inhibiting of glucagon release from cells, slowing of gastric emptying, decreasing appetite and increasing glucose-dependent insulin secretion (12, 46, 47)
Results are dose dependent, and the higher glutathione concentrations delivered by IV therapy can accelerate outcomes compared to injections alone
Other contributors to the pathogenesis of AD include synaptic dysfunction, neurotransmitter imbalance, neuroinflammation, insulin resistance, metabolic derangement, oxidative stress, mitochondrial dysfunction, and impaired autophagy [2]
2022 [cited 2024 Jan 24];2022
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