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A 10-year longitudinal follow-up study conducted at our research center on a cohort consisting of 159 patients with PCOS exhibited that long-term metformin treatment in overweight-obese women with PCOS led to a reduction and stabilization of body weight ( The weight trajectory after discontinuation of short-term semaglutide treatment in obese women with PCOS who continued metformin treatment has not yet been evaluated, so we can only provide a comparison with the general population from the STEP 1 extension study

It uses a 5% concentration of L-ascorbic acid to brighten and fade dark spots, but at a level thats far more tolerable than the usual 15 to 20% pure vitamin C formulas

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Ongoing research is also investigating whether GLP-1s may have neuroprotective effects, with early data suggesting possible benefits in Alzheimers and Parkinsons disease