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Common variants include: GSTM1 null : 40-50% of population-reduced capacity to neutralize environmental toxins GSTP1 variants : Impaired detoxification of carcinogens 6

Additional investigation into how glutamine metabolism affects macrophage activity may lead to the discovery of novel targets and therapeutic approaches for cancer

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Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome