According to the AIE mechanism, the fluorescence of these dyes can be turned on/off if the analyte can alter the aggregation behavior (solubility) or the intramolecular motions of the fluorescent species 55,56
By way of non-limiting examples, the formulations are administered as otic drops, as intratympanic injections, as foams or as otic paints
In this review, we discuss in detail the mechanisms and potential effects of these emerging therapies, which focus on their anti-inflammatory effects, enhancement of mucociliary clearance, and anti-infectious effects
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