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Figure taken pending permission from www.thyroidmanager.org Figure 4: Patient with pretibial myxedema

Patients who internalize it are more likely to discontinue treatment prematurely, against clinical guidance, in an attempt to prove something that was never a legitimate treatment benchmark to begin with

This may be connected to: immune activation reactive oxygen species mitochondrial dysfunction chronic inflammation pain-related nervous system stress GLP-1 medications may help by reducing oxidative stress and improving metabolic function, which may translate into improved energy for some women

Compounded GLP-1 receptor agonists (e.g., semaglutide or tirzepatide) should not be described as the same as FDA-approved products and must not be marketed as such