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Headache in the first 1-2 doses sometimes attributed by community sources to vasodilatory effects

While this can result in improved blood sugar levels and weight loss, it can also cause gastrointestinal (GI) side effects, such as nausea

The reality is that the name brand Wegovy can cost upwards of $1,300 per month without insurance and even with insurance, coverage is spotty at best

The GLP-1 agonist, exenatide, increased fasting EF via endothelial nitric oxide (NO) synthase (eNOS) activation, nitric oxide (NO) production in endothelial cells, induced dose-dependent vasorelaxation, and reduced high-glucose or lipid-induced endothelial dysfunction in arterioles ex vivo [64]