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Many drugs used to treat obesity in the past have been discontinued because of their potential to be abused and their toxicities [20-27] (Table 1 )

This is one of the reasons the field has paid such close attention to cysteine pools across decades of research

The sublingual mucosathe thin tissue beneath the tongueis highly vascularised and drains directly into the sublingual vein, which empties into the internal jugular vein and then the superior vena cava

The drug is composed of inactivated IFN- coupled to the keyhole limpet haemocyanin protein and when injected, leads to induction of polyclonal anti-IFN responses with transient immunity against all 13 subtypes of interferon alpha