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Author(s): 1Department of Biology, Arsanjan Branch, Islamic Azad University, Arsanjan, Iran 2Department of Physiology, Arak University of Medical Sciences, Arak, Iran 3Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran Zahedan Journal of Research in Medical Sciences:Vol
Clinical studies have shown that individuals using semaglutide experience substantial weight loss, often exceeding that achieved with other medications
What the study reinforces: There is no universal age limit for stopping MHT Starting HT later in life is riskier than earlier initiation Duration, age, and overall health matter a lot Ongoing reassessment is essential Non-hormonal options should always be part of the conversation There are also clear medical reasons not to use MHT, including: Personal (not familial) history of breast cancer (especially hormone-receptorpositive) Estrogen-dependent cancers (including endometrial cancer unless carefully cleared) Unexplained vaginal bleeding History of blood clots (DVT/PE) or known thrombophilia Prior stroke or heart attack Active liver disease Additional elevated-risk profiles include high cardiovascular risk, migraine with aura, obesity, and smoking
