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In the face of foam cell buildup and excessive cell death, efferocytes can become overwhelmed, leading to the loss of atheroprotective effector functions, cell death, and the release of pro-inflammatory DAMPs, which all augment the proatherogenic environment 2

To further explore differences between the models, and the potential for identifying novel functions, mitochondrial FP genes were compared to other sources of mitochondrial genes beyond the high confidence GO annotations used for classifier training

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