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This Review profiles established and emerging GLP-1-based medicines, discussing optimization of pharmacokinetics and tolerability, engagement of new therapeutically useful pathways and safety aspects

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Epidemiological data indicate that approximately 7 million people worldwide are affected by PD, a figure projected to rise to 12 million by 2040 (Tichelaar et al., 2023)

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Co-administration with sildenafil enhanced erectile activity compared to sildenafil alone, offering a potential alternative for patients with inadequate single-therapy responses (6)

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