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In addition, it can reduce the activation of transcription factors NF-B which is responsible for the initiation of inflammatory process and causes downregulation of IL-10 mRNA and protein expression in NAC-treated cells which cause further modification of the inflammatory cytokine profile [56, 65]
Bridging butyrate and protein post-translational modification Studies have extensively investigated how butyrate mediates physiological effects by activating GPCRs and inhibiting HDACs
ESHRE guideline: management of women with premature ovarian insufficiency [J]
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