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Additionally, data from a Phase I clinical trial (NCT02861300) indicated that the combination of CB-839 and capecitabine which is a prodrug of 5-FU, was well tolerated by CRC patients at bioactive doses

It is a designation used primarily by the FDA (Food and Drug Administration) for products, often in vitro diagnostic (IVD) components like reagents or instruments, that are in the laboratory research phase of development and are not intended for clinical diagnostic use

The chemotherapy drug GEM further induces USP8 expression, leading to increased stability and expression of NRF2

Conveniently situated for patients from Miracle Mile, La Brea, Beverly Grove, and surrounding areas, our Culver City clinic is easily accessible and centrally located near major freeways