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Contrave is FDA-approved for chronic weight management in adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher with at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol

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Although ibuprofen is available over the counter, the FDA warns that it can cause serious side effects including stomach bleeding, kidney damage and cardiovascular complications especially when used at high doses or for long periods