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We have previously used acetaldehyde to stimulate Hepatic Stellate cell-T6 (HSC-T6) cells in rats to establish an in vitro model of alcoholic liver fibrosis, and the results implicated the cAMP/PKA/SRC/ERK1/2/P38 MAPK signaling pathway as playing a key role, confirming the involvement of the adenosine signaling pathway in alcoholic liver fibrosis (Wang et al., 2014

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Science 381, 13081311

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E.PetrinovicM

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Copper-peptide-treated dermal fibroblasts showed decreased TGF-beta1 secretion

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