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the compound improved decline in several behavioural tasks: the Morris water maze, tilted beam walking and lateral push test

The identity of these derived cell lines was verified by confirmation of their parental origin and by validation of the intended genetic modifications, rather than by independent STR profiling

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Top-line results showed that on average, people who switched to orforglipron from semaglutide had a superior percent maintenance of body weight reduction, showing that subjects held onto their earlier weight loss compared to those who previously reached a body weight plateau