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Effects of GH on urea, glucose and lipid metabolism, and insulin sensitivity during fasting in GH-deficient patients

Specifically, HC induced a significant change in 15 proteins (i.e., 9 and 6 up- and down-regulated, respectively) involved in autophagy, including the down-regulation of NPC1 (Nieman-Pick type C) and QSOX1 (quiescin sulfhydryl oxidase 1) and the up-regulation of HMOX1 (heme oxygenase 1) and KDM4A (lysine demethylase 4A)

During the first couple of weeks, some patients report: Better skin hydration A healthier-looking glow Calmer, more refreshed-looking skin Early improvement in overall skin texture These early changes are consistent with GHK-Cus studied role in skin support and repair