T3 directly regulates hair follicle cycling, and even subclinical thyroid dysfunction, levels that fall within the "normal" range but sit at the lower end, can push follicles into premature telogen
This shows that non-injectable options are possible, but it comes with very specific instructions (like taking it on an empty stomach) to ensure absorption
For example, GLP-1R/GIPR dual agonists have demonstrated superior glucose-lowering and weight-loss effects in the treatment of diabetes and obesity
Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA