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Enhances Muscle Preservation By inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), it enhances cellular energy expenditure, encouraging the body to utilize stored fat as an energy source rather than breaking down muscle tissue

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Canonical Wnt signalling and mitochondrial H 2 O 2 production was also downregulated in a mouse model with TFAM KO, with subsequent defects in epidermal differentiation due to the inhibition of Notch signalling 132

Schmidt BM, Martin N, Georgens AC, Tillmann HC, Feuring M, Christ M, et al