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A smaller placebo-controlled trial showed that oral administration of 300 mg/day of coenzyme Q 10 for 48 to 96 months moderately improved motor symptoms in treated patients (with Levodopa) with re-emerging symptoms but not in patients at an early stage of the disease (67)

It exists in virtually every cell, with the highest concentrations found in the liver (up to 10 mM), where it plays a central role in detoxification, and in the lungs, kidneys, and brain [2][3]

Moderate physical activity strengthens the cardiovascular system, while excessive training leads to overuse injuries and systemic stress

Z.WuJ.et al (2021)