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doi: 10.1556/1886.2019.00016 87 ZhangHMWakisakaNMaedaOYamamotoT

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11,12 This ethnic selectivity may be explained by the fact that Europeans have a low prevalence of this particular HLA allele, 0.1%, compared to individuals with Southeast Asian ancestry (4.8%-12.8%), making the numbers needed to detect a statistically significant difference difficult to obtain