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Thus, suggesting that while individually, the DVC and the hypothalamus, appear to be sufficient to mediate the effects of GLP-1R agonists on energy balance, activation of multiple GLP-1R-responsive sites in the brain is necessary for endogenous GLP-1R regulation of feeding

Two standout topicals we often discuss with patients are GHK-Cu (the copper-binding regenerative peptide) and tretinoin combined with niacinamide

J Alzheimers Dis 7:4561

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