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1 1 2 Weight loss outcomes by engagement quartile *Based on a January 2026 analysis of 14,210 Noom GLP-1 Rx program members who joined between December 2024 and February 2025 and logged weight during a measurement week (4, 8, 16, 40 weeks) Total months persisted by engagement quartile *Based on a January 2026 analysis of 30,239 Noom GLP-1 Rx program members who joined between December 2024 and February 2025 Frequently Asked Questions Weight Loss and Engagement: January 2026 analysis of 14,203 Noom GLP-1 Rx Program members who started a GLP-1Rx plan between December 2024 and February 2025 and logged weight during a measurement week (4, 8, 16, 40 weeks)

68,69 Both MTHFD2 and MTHFD1 are markedly elevated and correlated with poor survival across human cancers

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Clinical data shows that approximately 2530% of patients experience nausea in the first week, with most cases resolving naturally within 714 days