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Is it safe to take tirzepatide (glucagon-like peptide-1 (GLP-1) receptor agonist) with Nicotinamide adenine dinucleotide (NAD) and Vitamin B12 supplements?

The Lean Mass Problem This is the conversation that is not happening in most prescribing offices

Int Immunopharmacol 115:109653 Little M, Dutta M, Li H et al (2022) Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut Microbiome using genetically modified mice

Significant nephrotoxic drugs include acetaminophen, NSAIDs, salicylates, aminoglycoside antibiotics, some antiviral drugs, some diabetes medications (GLP-1 agonists), and some chemotherapy drugs