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persistent or severe diarrhea warrants medical consultation Vomiting may occur particularly in the first few weeks of treatment Constipation affects some patients, potentially requiring dietary modifications or over-the-counter remedies Abdominal pain or discomfort usually mild and transient Decreased appetite an expected pharmacological effect that contributes to weight reduction These gastrointestinal effects are generally dose-dependent and tend to diminish over time as the body adapts to the medication

Once the patient consents to the plan, the next steps involve implementation, routine monitoring and support, and review of the plan

Ongoing monitoring typically includes repeat HbA1c at 12 weeks post-initiation and every 3 to 6 months thereafter, along with periodic renal function checks