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This parasites eggs are able to live for years, extremely resistant to many disinfectants, and cause serious infections in humans with poor treatment options

doi:10.1016/j.jagp.2016.01.134 Bilyukov RG, Nikolov MS, Pencheva VP, et al

J Pineal Res 48(1):7280 Chang F, Steelman LS, Lee JT, Shelton JG, Navolanic PM, Blalock WL et al (2003) Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention

Together, these studies argue that FSP1 can represent (1) a context-dependent essentiality (for example, metastatic niches) and/or (2) a stand-alone oxidative defense node that becomes rate limiting for tumor survival under physiological stressors encountered in vivo