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"Given their side effects, we assume that they are steroids," she told AFP, adding that prolonged use in high doses can cause depigmentation, diabetes and hypertension

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In the 1920s she began to investigate the production of insulin with August after she developed the disease herself

Other reported effects include: Headaches and dizziness Nausea and gastrointestinal discomfort Allergic reactions to B12 formulations (rare) If you experience symptoms suggesting a severe allergic reaction (difficulty breathing, severe rash, swelling of face/throat), seek emergency medical attention immediately by calling 999 or attending A&E